- MXIPr (3-MeO-2'-Oxo-PCIPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine) is a dissociative drug of the arylcyclohexylamine class acting as an NMDA receptor antagonist.
- This designer drug first appeared in 2020 as a research substance developed as a replacement for MXE.
Chemistry
- MXIPr is a derivative of drugs such as ketamine and methoxetamine.
- MXIPr contains an isopropyl group on the nitrogen atom of the molecule and an oxygen atom at the 2' position of the cyclohexyl ring, as well as a methoxy group at the 3 position of the phenyl ring.
Pharmacology
- The data on the toxicological and farmcological properties of MXIPr are incomplete.
- Studies in mice have shown that MXIPr acts as an NMDA receptor antagonist and is also a serotonin reuptake inhibitor. This drug causes dissociative, sedative and euphoric effects.
- Dosage:
- Threshold 5 mg
- Light 10 - 20 mg
- Common 20 - 40 mg
- Strong 40 - 60 mg
- Heavy 60 mg +
- Exposure time:
- Total 2 - 5 hours
- Onset 20 - 60 minutes
- After effects 4 - 48 hours
Legal status
- DE: NpSG (Industrial and scientific use only)
- UK: Class B
- CA: Schedule I
- Hungary: Not legal
Technical Information:
- Product Name: MXIPr
- Synonyms: 3-MeO-2'-Oxo-PCIPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine
- CAS: 2666932-55-2
- IUPAC: 2-(3-methoxyphenyl)-2-(propan-2-ylamino)cyclohexan-1-one
- 2-(isopropylamino)-2-(3-methoxyphenyl)cyclohexan-1-one
- Molecular Formula: C₁₆H₂₃NO₂
- Molecular Weight: 261.36 g/mol
- Purity: 98.0 % min.
- Formulations: A crystalline solid
- Solubility:
- DMF: 20 mg/ml
- MSO: 10 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): 2 mg/ml
- InChI: InChI=1S/C16H23NO2/c1-12(2)17-16(10-5-4-9-15(16)18)13-7-6-8-14(11-13)19-3/h6-8,11-12,17H,4-5,9-10H2,1-3H3
- InChIKey: FTQIVDGNXPEKP-UHFFFAOYSA-N
- SMILES: CC(C)NC1(CCCCC1=O)C2=CC(=CC=C2)OC
- Storage: -20°C
- Stability: ≥ 4 years
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